Northern Gritstone, the life sciences and deeptech venture capital firm, has announced the first £20 million investment into its one-year rolling close, building on the company’s £362 million of permanent capital.

The additional £20 million investment comes from existing Northern Gritstone shareholders including the British Business Bank and Andrew Law, CEO of hedge fund Caxton Associates, increasing their respective commitments to the company.

Over the course of 2026, Northern Gritstone is seeking to raise additional capital and this close, bringing its permanent capital to £382 million, marks the start of that program.

£10 million of the new funding commitment comes from the British Business Bank, bringing its total investment in Northern Gritstone to date to £40 million.

Many of Northern Gritstone’s portfolio companies are spinouts from the Northern Arc universities of Leeds, Liverpool, Manchester, and Sheffield, which combined generate close to £800 million in research funding annually.

The Northern Arc universities represent one of four globally competitive centres alongside Oxford, Cambridge and London, which together form the UK’s “Technology Diamond.”

Active since May 2022, Northern Gritstone sai it is “seizing the North of England’s innovation opportunity, investing in and scaling at speed deeptech and life sciences startups that solve global problems, with the potential to scale worldwide.”

The company has already made 50 investments in areas of development and future job creation in deeptech and life sciences, including semiconductor design and manufacturing; novel materials; secure computing; AI; healthtech; and gene therapies.

Northern Gritstone chair Jim O’Neill said: “We are very grateful for this further support from the British Business Bank and Andrew Law to continue developing global businesses in the North of England originating from our ‘Northern Arc’ university ecosystem.

“In this way, investors are contributing to future higher value-added activity and the North’s productivity”

Northern Gritstone CEO Duncan Johnson said: “This strong start to Northern Gritstone’s rolling close in today’s challenging fundraising environment shows the belief in innovation coming from the North of England. The region is now an integral part of the UK’s Technology Diamond, and we are proud to support the incredible talent of the North, helping to commercialise groundbreaking research into internationally commercial businesses.”

Christine Hockley, Managing Director and Head of Commercial Equity Funds, British Business Bank, said: “The UK’s universities are a powerhouse of breakthrough research, and Northern Gritstone plays a vital role in transforming world‑class research from the North of England into high‑potential, IP‑rich businesses. Our increased commitment reflects the Bank’s ambition to scale life sciences and deeptech businesses, which are critical to the UK’s future growth.”